Research and Reviews of Infectious Diseases

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Table of Content: Volume 1, Issue 1

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SHORT ARTICLE Pages 15-20

Mitochondrial Dysfunction Partially Explains Macrocytic Anemia in HIV-Exposed Uninfected Infants

Authors: Núria Rovira, Antoni Noguera-Julian, Constanza Morén, Glòria Garrabou, Rebeca Lahoz1, Òscar Miró, and Clàudia Fortuny

Abstract: Antiretroviral drugs are successfully used to prevent mother-to-child transmission of HIV worldwide. Hematologic and mitochondrial disturbances have been extensively reported among HIV-exposed uninfected (HEU) infants, but their pathogenic mechanisms remain largely unexplained.

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Case Report Pages 9-14

Liver Abscess and Septic Pulmonary Embolism. Description of Two Clinical Cases and Review of the Literature

Authors: Marta Lisa Graciaa, Paula Iruzubieta Cozb, Luis Martín Ramosb and Carlos Armiñanzas Castilloc

Abstract: Retrospective data was collected from all patients admitted for liver abscesses in the Marqués de Valdecilla University Hospital (Santander, Spain) between January 1, 1992 and December 31, 2012, and we analyzed which of them had also septic lung metastasis.

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Case Report Pages 6-8

Primary Varicella Zoster Virus Infection in an Eritrean Male Refugee in Denmark

Authors: Victor Dahl Mathiasen and Christian Wejse

Abstract: Primary infection with varicella zoster virus (VZV) in neonates, adults and in pregnancy may lead to severe disease and embryopathy. On the Northern hemisphere varicella is a mild childhood disease, but in tropical regions it typically occurs at later age and is more frequently observed among adolescents and adults. Disease presents with fever, malaise and a characteristic vesiculopapular rash (chickenpox) after an incubation period of 14 days on average.

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RESEARCH ARTICLE Pages 1-5

Comparative Effects of Repeated In Vitro Exposures of Plasmodium Falciparum to Sub-Lethal Doses of Pure Artemisinin and Artemisia Annua Phytochemical Blend

Authors: Lucy N Kangethe, Sabah Omar, Joseph K Nganga, Kimani Francis, Johnson Kinyua and Ahmed Hassanali

Abstract: Although tea infusions of Artemisia annua L. and Artemisia apiacea have been used > 2000 years in traditional Chinese medicine, there was no apparent resistance development to malaria parasites. Artemisinin was isolated and characterized in 1972 as the major potent antimalarial component of A. annua. This and a number of its derivatives have been promoted in combination therapy (ACTs) with other antimalarials with different mechanisms of action.

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